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E-64C

CAS No.
76684-89-4
Chemical Name:
E-64C
Synonyms
E-64C;NSC 694279;E-64c, EP 475;Loxistatin acid;anecarboxylicacid;ep475(enzymeinhibitor);Loxistatin Acid (E-64C);Inhibitorforthiolprotease;NSC 694279 Loxistatin Acid;E-64-c Loxistatin acid NSC 694279
CBNumber:
CB4425580
Molecular Formula:
C15H26N2O5
Molecular Weight:
314.38
MDL Number:
MFCD00132882
MOL File:
76684-89-4.mol
Last updated:2023-05-18 11:30:58

E-64C Properties

storage temp. Sealed in dry,Store in freezer, under -20°C
solubility ≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form White to off-white solid
InChIKey SCMSYZJDIQPSDI-SRVKXCTJSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
RTECS  RR0404200
HS Code  29241990

E-64C price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007964 E-64c ≥98% 76684-89-4 1mg $62 2024-03-01 Buy
Cayman Chemical 10007964 E-64c ≥98% 76684-89-4 5mg $270 2024-03-01 Buy
Cayman Chemical 10007964 E-64c ≥98% 76684-89-4 10mg $477 2024-03-01 Buy
Cayman Chemical 10007964 E-64c ≥98% 76684-89-4 25mg $1041 2024-03-01 Buy
TRC E100495 E-64c 76684-89-4 25mg $875 2021-12-16 Buy
Product number Packaging Price Buy
10007964 1mg $62 Buy
10007964 5mg $270 Buy
10007964 10mg $477 Buy
10007964 25mg $1041 Buy
E100495 25mg $875 Buy

E-64C Chemical Properties,Uses,Production

Description

E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.

Uses

E-64c is a cysteine protease inhibitor used for detecting autophagy in plants.

Definition

ChEBI: E-64c is a leucine derivative.

target

cathepsins B

E-64C Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 113)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58

View Lastest Price from E-64C manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
E-64C;NSC 694279 Loxistatin Acid pictures 2020-01-08 E-64C;NSC 694279 Loxistatin Acid
76684-89-4
US $0.01 / KG 1KG 98%; 99% 1kg;10kg; 25kg Career Henan Chemical Co

E-64C Spectrum

(2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE (2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE (2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid 2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)- Loxistatin Acid (E-64C) NSC 694279 E-64c, EP 475 (1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE E-64C L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE (+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir (2s-(2-alpha,3-beta(r*)))-mino)carbonyl) anecarboxylicacid ep475(enzymeinhibitor) oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a (2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL Inhibitorforthiolprotease (2S)-3β-[[[(S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2α-oxiranecarboxylic acid (2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid Loxistatin acid E-64-c Loxistatin acid NSC 694279 NSC 694279 Loxistatin Acid NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C 76684-89-4 BioChemical Calpain A to C Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme Enzyme Inhibitors Biochemicals and Reagents Pepetides Inhibitors peptides